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Intravenous ganaxolone in pediatric super-refractory status epilepticus: A single hospital experience
Synaptic GABA(A) receptor (GABA(A)R) internalization contributes to the drug resistant nature of super-refractory status epilepticus (SRSE). Ganaxolone is a 3β-methylated synthetic analog of the endogenous neuroactive steroid, allopregnanolone, that has positive allosteric modulatory activity on syn...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9619166/ https://www.ncbi.nlm.nih.gov/pubmed/36325100 http://dx.doi.org/10.1016/j.ebr.2022.100567 |