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Intravenous ganaxolone in pediatric super-refractory status epilepticus: A single hospital experience

Synaptic GABA(A) receptor (GABA(A)R) internalization contributes to the drug resistant nature of super-refractory status epilepticus (SRSE). Ganaxolone is a 3β-methylated synthetic analog of the endogenous neuroactive steroid, allopregnanolone, that has positive allosteric modulatory activity on syn...

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Detalles Bibliográficos
Autores principales:	Singh, Rani K., Singh, Rajdeep, Stewart, Alejandra, Van Poppel, Katherine, Klinger, Sarah, Hulihan, Joseph, Van Heusen, Heather, Vaitkevicius, Henrikas, Gasior, Maciej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9619166/ https://www.ncbi.nlm.nih.gov/pubmed/36325100 http://dx.doi.org/10.1016/j.ebr.2022.100567

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