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Evaluation of clonal hematopoiesis in pediatric ADA-SCID gene therapy participants

Autologous stem cell transplant with gene therapy (ASCT-GT) provides curative therapy while reducing pretransplant immune-suppressive conditioning and eliminating posttransplant immune suppression. Clonal hematopoiesis of indeterminate potential (CHIP)–associated mutations increase and telomere leng...

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Detalles Bibliográficos
Autores principales: White, Shanna L., Lee, Thomas D., Toy, Traci, Carroll, Judith E., Polsky, Lilian, Campo Fernandez, Beatriz, Davila, Alejandra, Kohn, Donald B., Chang, Vivian Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9619180/
https://www.ncbi.nlm.nih.gov/pubmed/35914227
http://dx.doi.org/10.1182/bloodadvances.2022007803