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Identification of MRAP protein family as broad‐spectrum GPCR modulators

BACKGROUND: The melanocortin receptor accessory proteins (MRAP1 and MRAP2) are well‐known endocrine regulators for the trafficking and signalling of all five melanocortin receptors (MC1R–MC5R). The observation of MRAP2 on regulating several non‐melanocortin G protein‐coupled receptors (GPCRs) has be...

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Detalles Bibliográficos
Autores principales: Wang, Meng, Wang, Xiaozhu, Jiang, Bopei, Zhai, Yue, Zheng, Jihong, Yang, Liu, Tai, Xiaolu, Li, Yunpeng, Fu, Shaliu, Xu, Jing, Lei, Xiaowei, Kuang, Zhe, Zhang, Cong, Bai, Xuanxuan, Li, Mingyu, Zan, Tao, Qu, Shen, Li, Qingfeng, Zhang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9619224/
https://www.ncbi.nlm.nih.gov/pubmed/36314066
http://dx.doi.org/10.1002/ctm2.1091