Cargando…
Identification of MRAP protein family as broad‐spectrum GPCR modulators
BACKGROUND: The melanocortin receptor accessory proteins (MRAP1 and MRAP2) are well‐known endocrine regulators for the trafficking and signalling of all five melanocortin receptors (MC1R–MC5R). The observation of MRAP2 on regulating several non‐melanocortin G protein‐coupled receptors (GPCRs) has be...
Autores principales: | Wang, Meng, Wang, Xiaozhu, Jiang, Bopei, Zhai, Yue, Zheng, Jihong, Yang, Liu, Tai, Xiaolu, Li, Yunpeng, Fu, Shaliu, Xu, Jing, Lei, Xiaowei, Kuang, Zhe, Zhang, Cong, Bai, Xuanxuan, Li, Mingyu, Zan, Tao, Qu, Shen, Li, Qingfeng, Zhang, Chao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9619224/ https://www.ncbi.nlm.nih.gov/pubmed/36314066 http://dx.doi.org/10.1002/ctm2.1091 |
Ejemplares similares
-
Determination of the Interaction and Pharmacological Modulation of MCHR1 Signaling by the C-Terminus of MRAP2 Protein
por: Wang, Meng, et al.
Publicado: (2022) -
Identification of novel GPCR partners of the central melanocortin signaling
por: Li, Yunpeng, et al.
Publicado: (2021) -
Functional Characterization of the Internal Symmetry of MRAP2 Antiparallel Homodimer
por: Wang, Meng, et al.
Publicado: (2021) -
Pharmacological Modulation of Melanocortin 1 Receptor Signaling by Mrap Proteins in Xenopus tropicalis
por: Tai, Xiaolu, et al.
Publicado: (2022) -
Reversion of MRAP2 Protein Sequence Generates a Functional Novel Pharmacological Modulator for MC4R Signaling
por: Xu, Jing, et al.
Publicado: (2022)