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MLK3 silence suppressed osteogenic differentiation and delayed bone formation via influencing the bone metabolism and disturbing MAPK signaling

BACKGROUND: Mixed lineage kinase 3 (MLK3) is a member of a serine/threonine MAP3K family, and it has been demonstrated to play critical roles in various biological activities and disease progression. Previous studies showed that impaired skeletal mineralization and spontaneous tooth fracture in the...

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Detalles Bibliográficos
Autores principales: Yang, Xiao, Mai, Yong-xin, Wei, Lan, Peng, Li-yang, Pang, Feng-xiang, Wang, Ling-jun, Li, Zhi-peng, Zhang, Jin-fang, Jin, An-min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9619354/
https://www.ncbi.nlm.nih.gov/pubmed/36381243
http://dx.doi.org/10.1016/j.jot.2022.07.003