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Lectin-Targeted Prodrugs Activated by Pseudomonas aeruginosa for Self-Destructive Antibiotic Release

[Image: see text] Chronic Pseudomonas aeruginosa infections are characterized by biofilm formation, a major virulence factor of P. aeruginosa and cause of extensive drug resistance. Fluoroquinolones are effective antibiotics but are linked to severe side effects. The two extracellular P. aeruginosa-...

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Detalles Bibliográficos
Autores principales: Meiers, Joscha, Rox, Katharina, Titz, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9619409/
https://www.ncbi.nlm.nih.gov/pubmed/36201248
http://dx.doi.org/10.1021/acs.jmedchem.2c01214