Rapid Selection of Sotrovimab Escape Variants in Severe Acute Respiratory Syndrome Coronavirus 2 Omicron-Infected Immunocompromised Patients

BACKGROUND: Monoclonal antibodies (mAbs) that target severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are predominantly less effective against Omicron variants. Immunocompromised patients often experience prolonged viral shedding, resulting in an increased risk of viral escape. METHODS:...

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Detalles Bibliográficos
Autores principales: Gliga, Smaranda, Lübke, Nadine, Killer, Alexander, Gruell, Henning, Walker, Andreas, Dilthey, Alexander T, Thielen, Alexander, Lohr, Carolin, Flaßhove, Charlotte, Krieg, Sarah, Pereira, Joanna Ventura, Seraphin, Tobias Paul, Zaufel, Alex, Däumer, Martin, Orth, Hans-Martin, Feldt, Torsten, Bode, Johannes G, Klein, Florian, Timm, Jörg, Luedde, Tom, Jensen, Björn-Erik Ole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9619606/
https://www.ncbi.nlm.nih.gov/pubmed/36189631
http://dx.doi.org/10.1093/cid/ciac802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9619606/
https://www.ncbi.nlm.nih.gov/pubmed/36189631
http://dx.doi.org/10.1093/cid/ciac802

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