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Sialidase Inhibitors with Different Mechanisms

[Image: see text] Sialidases, or neuraminidases, are enzymes that catalyze the hydrolysis of sialic acid (Sia)-containing molecules, mostly removal of the terminal Sia (desialylation). By desialylation, sialidase can modulate the functionality of the target compound and is thus often involved in bio...

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Detalles Bibliográficos
Autores principales: Keil, Joseph M., Rafn, Garrett R., Turan, Isaac M., Aljohani, Majdi A., Sahebjam-Atabaki, Reza, Sun, Xue-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620260/
https://www.ncbi.nlm.nih.gov/pubmed/36252951
http://dx.doi.org/10.1021/acs.jmedchem.2c01258