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Quercitrin neutralizes sPLA2IIa activity, reduces the inflammatory IL-6 level in PC3 cell lines, and exhibits anti-tumor activity in the EAC-bearing mice model

Human phospholipase A(2) group IIa (sPLA(2)IIa) is an inflammatory enzyme that plays a significant role in tumorigenesis. Inhibiting the sPLA(2)IIa enzyme with an effective molecule can reduce the inflammatory response and halt cancer progression. The present study evaluates quercitrin, a biflavonoi...

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Detalles Bibliográficos
Autores principales: Sophiya, P., Urs, Deepadarshan, K. Lone, Jafar, Giresha, A. S., Krishna Ram, H., Manjunatha, J. G., El-Serehy, Hamed A., Narayanappa, M., Shankar, J., Bhardwaj, Ragini, Ahmad Guru, Sameer, Dharmappa, K. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620381/
https://www.ncbi.nlm.nih.gov/pubmed/36324674
http://dx.doi.org/10.3389/fphar.2022.996285