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Quercitrin neutralizes sPLA2IIa activity, reduces the inflammatory IL-6 level in PC3 cell lines, and exhibits anti-tumor activity in the EAC-bearing mice model
Human phospholipase A(2) group IIa (sPLA(2)IIa) is an inflammatory enzyme that plays a significant role in tumorigenesis. Inhibiting the sPLA(2)IIa enzyme with an effective molecule can reduce the inflammatory response and halt cancer progression. The present study evaluates quercitrin, a biflavonoi...
Autores principales: | Sophiya, P., Urs, Deepadarshan, K. Lone, Jafar, Giresha, A. S., Krishna Ram, H., Manjunatha, J. G., El-Serehy, Hamed A., Narayanappa, M., Shankar, J., Bhardwaj, Ragini, Ahmad Guru, Sameer, Dharmappa, K. K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620381/ https://www.ncbi.nlm.nih.gov/pubmed/36324674 http://dx.doi.org/10.3389/fphar.2022.996285 |
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