Cargando…
Dopamine D2 receptors bidirectionally regulate striatal enkephalin expression: Implications for cocaine reward
Low dopamine D2 receptor (D2R) availability in the striatum can predispose for cocaine abuse; though how low striatal D2Rs facilitate cocaine reward is unclear. Overexpression of D2Rs in striatal neurons or activation of D2Rs by acute cocaine suppresses striatal Penk mRNA. Conversely, low D2Rs in D2...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620395/ https://www.ncbi.nlm.nih.gov/pubmed/36170833 http://dx.doi.org/10.1016/j.celrep.2022.111440 |