Cargando…
Mediating and maintaining methylation while minimizing mutation: Recent advances on mammalian DNA methyltransferases
Mammalian genomes are methylated on carbon-5 of many cytosines, mostly in CpG dinucleotides. Methylation patterns are maintained during mitosis via DNMT1, and regulatory factors involved in processes that include histone modifications. Methylation in a sequence longer than CpG can influence the bind...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620438/ https://www.ncbi.nlm.nih.gov/pubmed/35914495 http://dx.doi.org/10.1016/j.sbi.2022.102433 |