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Mediating and maintaining methylation while minimizing mutation: Recent advances on mammalian DNA methyltransferases
Mammalian genomes are methylated on carbon-5 of many cytosines, mostly in CpG dinucleotides. Methylation patterns are maintained during mitosis via DNMT1, and regulatory factors involved in processes that include histone modifications. Methylation in a sequence longer than CpG can influence the bind...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620438/ https://www.ncbi.nlm.nih.gov/pubmed/35914495 http://dx.doi.org/10.1016/j.sbi.2022.102433 |