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Therapeutic modulation of gene expression in the disease state: Treatment strategies and approaches for the development of next-generation of the epigenetic drugs

Epigenetic dysregulation is an important determinant of many pathological conditions and diseases. Designer molecules that can specifically target endogenous DNA sequences provide a means to therapeutically modulate gene function. The prokaryote-derived CRISPR/Cas editing systems have transformed ou...

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Detalles Bibliográficos
Autores principales: Rittiner, Joseph, Cumaran, Mohanapriya, Malhotra, Sahil, Kantor, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620476/
https://www.ncbi.nlm.nih.gov/pubmed/36324900
http://dx.doi.org/10.3389/fbioe.2022.1035543