Bone-targeting delivery of platelet lysate exosomes ameliorates glucocorticoid-induced osteoporosis by enhancing bone-vessel coupling

BACKGROUND: Glucocorticoids (GCs) overuse is associated with decreased bone mass and osseous vasculature destruction, leading to severe osteoporosis. Platelet lysates (PL) as a pool of growth factors (GFs) were widely used in local bone repair by its potent pro-regeneration and pro-angiogenesis. How...

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Detalles Bibliográficos
Autores principales: Zheng, Gang, Ma, Hai-Wei, Xiang, Guang-Heng, He, Gao-Lu, Cai, Han-Chen, Dai, Zi-Han, Chen, Yan-Lin, Lin, Yan, Xu, Hua-Zi, Ni, Wen-Fei, Xu, Cong, Liu, Hai-Xiao, Wang, Xiang-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620632/
https://www.ncbi.nlm.nih.gov/pubmed/36310171
http://dx.doi.org/10.1186/s12951-022-01400-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620632/
https://www.ncbi.nlm.nih.gov/pubmed/36310171
http://dx.doi.org/10.1186/s12951-022-01400-1

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