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Loss of T cell tolerance in the skin following immunopathology is linked to failed restoration of the dermal niche by recruited macrophages
T cell pathology in the skin leads to monocyte influx, but we have little understanding of the fate of recruited cells within the diseased niche, or the long-term impact on cutaneous immune homeostasis. By combining a murine model of acute graft-versus-host disease (aGVHD) with analysis of patient s...
Autores principales: | West, Heather C., Davies, James, Henderson, Stephen, Adegun, Oluyori K., Ward, Sophie, Ferrer, Ivana R., Tye, Chanidapa A., Vallejo, Andres F., Jardine, Laura, Collin, Matthew, Polak, Marta E., Bennett, Clare L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620741/ https://www.ncbi.nlm.nih.gov/pubmed/35584681 http://dx.doi.org/10.1016/j.celrep.2022.110819 |
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