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Integrating network pharmacology and an experimental validation strategy elucidates the protective effect and mechanism of callicarpa nudiflora against neuroinflammation

Abnormal activation of microglia promotes neuroinflammation (NI) in Alzheimer's disease (AD). Callicarpa nudiflora Hook et Arn. (CN) is a traditional Chinese herb with a wide range of clinical applications and definite anti-inflammatory effects. However, the anti-inflammatory action and mechani...

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Detalles Bibliográficos
Autores principales: Yang, Guodong, Liu, Yufu, Liu, Yonglin, Ma, Yu, Li, Yiguang, Chen, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620778/
https://www.ncbi.nlm.nih.gov/pubmed/36349022
http://dx.doi.org/10.1039/d2ra05143e