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PHi-C2: interpreting Hi-C data as the dynamic 3D genome state

SUMMARY: High-throughput chromosome conformation capture (Hi-C) is a widely used assay for studying the three-dimensional (3D) genome organization across the whole genome. Here, we present PHi-C2, a Python package supported by mathematical and biophysical polymer modeling that converts input Hi-C ma...

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Detalles Bibliográficos
Autores principales: Shinkai, Soya, Itoga, Hiroya, Kyoda, Koji, Onami, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620818/
https://www.ncbi.nlm.nih.gov/pubmed/36087002
http://dx.doi.org/10.1093/bioinformatics/btac613