Quantifying Oligomer Populations in Real Time during Protein Aggregation Using Single-Molecule Mass Photometry

[Image: see text] Protein aggregation is a hallmark of many neurodegenerative diseases. The early stages of the aggregation cascade are crucial because small oligomers are thought to be key neurotoxic species, but they are difficult to study because they feature heterogeneous mixtures of transient s...

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Detalles Bibliográficos
Autores principales: Paul, Simanta Sarani, Lyons, Aaron, Kirchner, Russell, Woodside, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620981/
https://www.ncbi.nlm.nih.gov/pubmed/36126253
http://dx.doi.org/10.1021/acsnano.2c05739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620981/
https://www.ncbi.nlm.nih.gov/pubmed/36126253
http://dx.doi.org/10.1021/acsnano.2c05739

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