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Quantifying Oligomer Populations in Real Time during Protein Aggregation Using Single-Molecule Mass Photometry
[Image: see text] Protein aggregation is a hallmark of many neurodegenerative diseases. The early stages of the aggregation cascade are crucial because small oligomers are thought to be key neurotoxic species, but they are difficult to study because they feature heterogeneous mixtures of transient s...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620981/ https://www.ncbi.nlm.nih.gov/pubmed/36126253 http://dx.doi.org/10.1021/acsnano.2c05739 |