Depletion of ALMS1 affects TGF-β signalling pathway and downstream processes such as cell migration and adhesion capacity

Background: ALMS1 is a ubiquitous gene associated with Alström syndrome (ALMS). The main symptoms of ALMS affect multiple organs and tissues, generating at last, multi-organic fibrosis in the lungs, kidneys and liver. TGF-β is one of the main pathways implicated in fibrosis, controlling the cell cyc...

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Detalles Bibliográficos
Autores principales: Bea-Mascato, Brais, Neira-Goyanes, Elena, Iglesias-Rodríguez, Antía, Valverde, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621122/
https://www.ncbi.nlm.nih.gov/pubmed/36325276
http://dx.doi.org/10.3389/fmolb.2022.992313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621122/
https://www.ncbi.nlm.nih.gov/pubmed/36325276
http://dx.doi.org/10.3389/fmolb.2022.992313

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