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Epigenetics in glaucoma: a link between DNA methylation and neurodegeneration

Normal-tension glaucoma is a form of optic nerve degeneration that is characterized by loss of retinal ganglion cells independent of eye pressure elevation. In this issue of the JCI, Pan et al. report the discovery in a Japanese family of a mutation in the METTL23 gene, which encodes a DNA methyltra...

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Detalles Bibliográficos
Autores principales: Liu, Wendy W., Sun, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621123/
https://www.ncbi.nlm.nih.gov/pubmed/36317630
http://dx.doi.org/10.1172/JCI163670