Effect of acute TLR4 inhibition on insulin resistance in humans

BACKGROUND: Studies in cell cultures and rodents suggest that TLR4 is involved in the pathogenesis of insulin resistance, but direct data in humans are limited. We tested the hypothesis that pharmacologic blockade of TLR4 with the competitive inhibitor eritoran would improve insulin resistance in hu...

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Detalles Bibliográficos
Autores principales: Liang, Hanyu, Sathavarodom, Nattapol, Colmenares, Claudia, Gelfond, Jonathan, Espinoza, Sara E., Ganapathy, Vinutha, Musi, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621129/
https://www.ncbi.nlm.nih.gov/pubmed/36066991
http://dx.doi.org/10.1172/JCI162291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621129/
https://www.ncbi.nlm.nih.gov/pubmed/36066991
http://dx.doi.org/10.1172/JCI162291

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