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Risk of advanced fibrosis in first-degree relatives of patients with nonalcoholic fatty liver disease

BACKGROUND: A pilot, single-center study showed that first-degree relatives of probands with nonalcoholic fatty liver disease (NAFLD) cirrhosis have a high risk of advanced fibrosis. We aimed to validate these findings using 2 independent cohorts from the US and Europe. METHODS: This prospective stu...

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Detalles Bibliográficos
Autores principales: Tamaki, Nobuharu, Ahlholm, Noora, Luukkonen, Panu K., Porthan, Kimmo, Sharpton, Suzanne R., Ajmera, Veeral, Kono, Yuko, Dave, Shravan, Ahmed, Aijaz, Sundaram, Vinay, Wilkinson, Michael J., Patton, Heather, Gupta, Hersh, Cervantes, Vanessa, Hernandez, Christie, Lopez, Scarlett J., Loomba, Ria, Baumgartner, Amanda, Richards, Lisa, Arkkila, Perttu E.T., Nemes, Katriina, Isoniemi, Helena, Yki-Järvinen, Hannele, Loomba, Rohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621132/
https://www.ncbi.nlm.nih.gov/pubmed/36317632
http://dx.doi.org/10.1172/JCI162513