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R-spondin/YAP axis promotes gastric oxyntic gland regeneration and Helicobacter pylori–associated metaplasia in mice

The stomach corpus epithelium is organized into anatomical units that consist of glands and pits. Mechanisms that control the cellular organization of corpus glands and enable their recovery upon injury are not well understood. R-spondin 3 (RSPO3) is a WNT-signaling enhancer that regulates stem cell...

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Detalles Bibliográficos
Autores principales: Fischer, Anne-Sophie, Müllerke, Stefanie, Arnold, Alexander, Heuberger, Julian, Berger, Hilmar, Lin, Manqiang, Mollenkopf, Hans-Joachim, Wizenty, Jonas, Horst, David, Tacke, Frank, Sigal, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621134/
https://www.ncbi.nlm.nih.gov/pubmed/36099044
http://dx.doi.org/10.1172/JCI151363