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Autophagic flux restoration enhances the antitumor efficacy of tumor infiltrating lymphocytes

BACKGROUND: Although adoptive cell therapy with tumor infiltrating lymphocytes (TILs) has mediated effective antitumor responses in several cancers, dysfunction and exhaustion of TILs significantly impair the therapeutic effect of TILs. Thus, it is essential to elucidate the exhausted characteristic...

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Detalles Bibliográficos
Autores principales: Zhang, Chaoting, Sun, Yizhe, Li, Shance, Shen, Luyan, Teng, Xia, Xiao, Yefei, Wu, Nan, Lu, Zheming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621197/
https://www.ncbi.nlm.nih.gov/pubmed/36307150
http://dx.doi.org/10.1136/jitc-2022-004868