MERS-CoV nsp1 regulates autophagic flux via mTOR signalling and dysfunctional lysosomes

Autophagy, a cellular surveillance mechanism, plays an important role in combating invading pathogens. However, viruses have evolved various strategies to disrupt autophagy and even hijack it for replication and release. Here, we demonstrated that Middle East respiratory syndrome coronavirus (MERS-C...

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Detalles Bibliográficos
Autores principales: Feng, Yujie, Pan, Zhaoyi, Wang, Zhihui, Lei, Zhengyang, Yang, Songge, Zhao, Huajun, Wang, Xueyao, Yu, Yating, Han, Qiuju, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Coronaviruses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621213/
https://www.ncbi.nlm.nih.gov/pubmed/36153658
http://dx.doi.org/10.1080/22221751.2022.2128434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621213/
https://www.ncbi.nlm.nih.gov/pubmed/36153658
http://dx.doi.org/10.1080/22221751.2022.2128434

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