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Machine learning advances the integration of covariates in population pharmacokinetic models: Valproic acid as an example

Background and Aim: Many studies associated with the combination of machine learning (ML) and pharmacometrics have appeared in recent years. ML can be used as an initial step for fast screening of covariates in population pharmacokinetic (popPK) models. The present study aimed to integrate covariate...

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Detalles Bibliográficos
Autores principales: Zhu, Xiuqing, Zhang, Ming, Wen, Yuguan, Shang, Dewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621318/
https://www.ncbi.nlm.nih.gov/pubmed/36324679
http://dx.doi.org/10.3389/fphar.2022.994665