Epstein–Barr virus infection, B‐cell dysfunction and other risk factors converge in gut‐associated lymphoid tissue to drive the immunopathogenesis of multiple sclerosis: a hypothesis

Multiple sclerosis is associated with Epstein–Barr virus (EBV) infection, B‐cell dysfunction, gut dysbiosis, and environmental and genetic risk factors, including female sex. A disease model incorporating all these factors remains elusive. Here, we hypothesise that EBV‐infected memory B cells (MBCs)...

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Detalles Bibliográficos
Autores principales: Leffler, Jonatan, Trend, Stephanie, Hart, Prue H, French, Martyn A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Theoretical Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621333/
https://www.ncbi.nlm.nih.gov/pubmed/36325491
http://dx.doi.org/10.1002/cti2.1418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621333/
https://www.ncbi.nlm.nih.gov/pubmed/36325491
http://dx.doi.org/10.1002/cti2.1418

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