Oxidation state-specific fluorescent copper sensors reveal oncogene-driven redox changes that regulate labile copper(II) pools

Copper is an essential metal nutrient for life that often relies on redox cycling between Cu(I) and Cu(II) oxidation states to fulfill its physiological roles, but alterations in cellular redox status can lead to imbalances in copper homeostasis that contribute to cancer and other metalloplasias wit...

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Detalles Bibliográficos
Autores principales: Pezacki, Aidan T., Matier, Carson D., Gu, Xingxing, Kummelstedt, Eric, Bond, Sarah E., Torrente, Laura, Jordan-Sciutto, Kelly L., DeNicola, Gina M., Su, Timothy A., Brady, Donita C., Chang, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Physical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621372/
https://www.ncbi.nlm.nih.gov/pubmed/36252013
http://dx.doi.org/10.1073/pnas.2202736119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621372/
https://www.ncbi.nlm.nih.gov/pubmed/36252013
http://dx.doi.org/10.1073/pnas.2202736119

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