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2-Bromopalmitate decreases spinal inflammation and attenuates oxaliplatin-induced neuropathic pain via reducing Drp1-mediated mitochondrial dysfunction

Oxaliplatin (OXA) is a third-generation platinum compound with clinical activity in multiple solid tumors. Due to the repetition of chemotherapy cycle, OXA-induced chronic neuropathy presenting as paresthesia and pain. This study explored the neuropathy of chemotherapy pain and investigated the anal...

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Detalles Bibliográficos
Autores principales: Dong, Zhi-Bin, Wang, Yu-Jia, Cheng, Meng-Lin, Wang, Bo-Jun, Lu, Hong, Zhu, Hai-Li, Liu, Ling, Xie, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621438/
https://www.ncbi.nlm.nih.gov/pubmed/36315519
http://dx.doi.org/10.1371/journal.pone.0275428