Optimal sequence-based design for multi-antigen HIV-1 vaccines using minimally distant antigens

The immense global diversity of HIV-1 is a significant obstacle to developing a safe and effective vaccine. We recently showed that infections established with multiple founder variants are associated with the development of neutralization breadth years later. We propose a novel vaccine design strat...

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Detalles Bibliográficos
Autores principales: Lewitus, Eric, Hoang, Jennifer, Li, Yifan, Bai, Hongjun, Rolland, Morgane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621458/
https://www.ncbi.nlm.nih.gov/pubmed/36315492
http://dx.doi.org/10.1371/journal.pcbi.1010624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621458/
https://www.ncbi.nlm.nih.gov/pubmed/36315492
http://dx.doi.org/10.1371/journal.pcbi.1010624

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