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Optimal sequence-based design for multi-antigen HIV-1 vaccines using minimally distant antigens
The immense global diversity of HIV-1 is a significant obstacle to developing a safe and effective vaccine. We recently showed that infections established with multiple founder variants are associated with the development of neutralization breadth years later. We propose a novel vaccine design strat...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621458/ https://www.ncbi.nlm.nih.gov/pubmed/36315492 http://dx.doi.org/10.1371/journal.pcbi.1010624 |