Loss of Integrin-Linked Kinase Sensitizes Breast Cancer to SRC Inhibitors

SRC is a nonreceptor tyrosine kinase with key roles in breast cancer development and progression. Despite this, SRC tyrosine kinase inhibitors have so far failed to live up to their promise in clinical trials, with poor overall response rates. We aimed to identify possible synergistic gene–drug inte...

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Detalles Bibliográficos
Autores principales: Beetham, Henry, Griffith, Billie G.C., Murina, Olga, Loftus, Alexander E.P., Parry, David A., Temps, Carolin, Culley, Jayne, Muir, Morwenna, Unciti-Broceta, Asier, Sims, Andrew H., Byron, Adam, Brunton, Valerie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Molecular Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621571/
https://www.ncbi.nlm.nih.gov/pubmed/34921014
http://dx.doi.org/10.1158/0008-5472.CAN-21-0373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621571/
https://www.ncbi.nlm.nih.gov/pubmed/34921014
http://dx.doi.org/10.1158/0008-5472.CAN-21-0373

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