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DPCfam: Unsupervised protein family classification by Density Peak Clustering of large sequence datasets
Proteins that are known only at a sequence level outnumber those with an experimental characterization by orders of magnitude. Classifying protein regions (domains) into homologous families can generate testable functional hypotheses for yet unannotated sequences. Existing domain family resources ty...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621593/ https://www.ncbi.nlm.nih.gov/pubmed/36260616 http://dx.doi.org/10.1371/journal.pcbi.1010610 |