Cargando…

DPCfam: Unsupervised protein family classification by Density Peak Clustering of large sequence datasets

Proteins that are known only at a sequence level outnumber those with an experimental characterization by orders of magnitude. Classifying protein regions (domains) into homologous families can generate testable functional hypotheses for yet unannotated sequences. Existing domain family resources ty...

Descripción completa

Detalles Bibliográficos
Autores principales: Russo, Elena Tea, Barone, Federico, Bateman, Alex, Cozzini, Stefano, Punta, Marco, Laio, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621593/
https://www.ncbi.nlm.nih.gov/pubmed/36260616
http://dx.doi.org/10.1371/journal.pcbi.1010610