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Integrated experimental-computational analysis of a HepaRG liver-islet microphysiological system for human-centric diabetes research

Microphysiological systems (MPS) are powerful tools for emulating human physiology and replicating disease progression in vitro. MPS could be better predictors of human outcome than current animal models, but mechanistic interpretation and in vivo extrapolation of the experimental results remain sig...

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Detalles Bibliográficos
Autores principales: Casas, Belén, Vilén, Liisa, Bauer, Sophie, Kanebratt, Kajsa P., Wennberg Huldt, Charlotte, Magnusson, Lisa, Marx, Uwe, Andersson, Tommy B., Gennemark, Peter, Cedersund, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621595/
https://www.ncbi.nlm.nih.gov/pubmed/36260620
http://dx.doi.org/10.1371/journal.pcbi.1010587