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Integrated experimental-computational analysis of a HepaRG liver-islet microphysiological system for human-centric diabetes research
Microphysiological systems (MPS) are powerful tools for emulating human physiology and replicating disease progression in vitro. MPS could be better predictors of human outcome than current animal models, but mechanistic interpretation and in vivo extrapolation of the experimental results remain sig...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621595/ https://www.ncbi.nlm.nih.gov/pubmed/36260620 http://dx.doi.org/10.1371/journal.pcbi.1010587 |