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SARS-CoV-2 Omicron BA.1 Challenge after Ancestral or Delta Infection in Mice

We assessed cross-reactivity to BA.1, BA.2, and BA.5 of neutralizing antibodies elicited by ancestral, Delta, and Omicron BA.1 SARS-CoV-2 infection in mice. Primary infection elicited homologous antibodies with poor cross-reactivity to Omicron strains. This pattern remained after BA.1 challenge, alt...

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Detalles Bibliográficos
Autores principales: Baz, Mariana, Deshpande, Nikita, Mackenzie-Kludas, Charlie, Mordant, Francesca, Anderson, Danielle, Subbarao, Kanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622237/
https://www.ncbi.nlm.nih.gov/pubmed/36191630
http://dx.doi.org/10.3201/eid2811.220718