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Clinical Factors Affecting the Serum Retention of a Teratogenic Etretinate after the Acitretin Administration
Etretinate, an acitretin metabolite, has a long retention duration in adipose tissues with a teratogenic potential. FDA advises a contraceptive period of at least three years after discontinuing acitretin. However, the effect of accumulated etretinate in adipose tissues on fetus is unknown. Although...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622308/ https://www.ncbi.nlm.nih.gov/pubmed/35871607 http://dx.doi.org/10.4062/biomolther.2022.069 |