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Clinical Factors Affecting the Serum Retention of a Teratogenic Etretinate after the Acitretin Administration

Etretinate, an acitretin metabolite, has a long retention duration in adipose tissues with a teratogenic potential. FDA advises a contraceptive period of at least three years after discontinuing acitretin. However, the effect of accumulated etretinate in adipose tissues on fetus is unknown. Although...

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Detalles Bibliográficos
Autores principales: Jeong, Jong Heon, Hyun, Gyu Hwan, Park, Yu Jeong, Kwon, Sung Won, Lee, Ai-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622308/
https://www.ncbi.nlm.nih.gov/pubmed/35871607
http://dx.doi.org/10.4062/biomolther.2022.069