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p38 MAPK Inhibitor NJK14047 Suppresses CDNB-Induced Atopic Dermatitis-Like Symptoms in BALB/c Mice

Atopic dermatitis (AD) is a chronic inflammatory skin disorder. Suppression of MAPKs and NF-κB is implicated as a vital mechanism of action of several traditional Chinese medicines for AD therapy. Although overexpression of MAPK mRNA in the skin tissue has been shown in the AD model, the roles of ea...

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Detalles Bibliográficos
Autores principales: Lee, Ju-Hyun, Son, Seung-Hwan, Kim, Nam-Jung, Im, Dong-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622309/
https://www.ncbi.nlm.nih.gov/pubmed/35788499
http://dx.doi.org/10.4062/biomolther.2022.024