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Synthetic Homoisoflavane Derivatives of Cremastranone Suppress Growth of Colorectal Cancer Cells through Cell Cycle Arrest and Induction of Apoptosis

Colorectal cancer is diagnosed as the third most prevalent cancer; thus, effective therapeutic agents are urgently required. In this study, we synthesized six homoisoflavane derivatives of cremastranone and investigated their cytotoxic effects on the human colorectal cancer cell lines HCT116 and LoV...

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Detalles Bibliográficos
Autores principales: Shin, Ha-Eun, Lee, Seul, Choi, Yeram, Park, Sangkyu, Kwon, Sangil, Choi, Jun-Kyu, Seo, Seung-Yong, Lee, Younghee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622311/
https://www.ncbi.nlm.nih.gov/pubmed/35934668
http://dx.doi.org/10.4062/biomolther.2022.090