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AT9283, 1-Cyclopropyl-3-(3-(5-(Morpholinomethyl)-1H-Benzo[d] Imidazole-2-yl)-1H-Pyrazol-4-yl) Urea, Inhibits Syk to Suppress Mast Cell-Mediated Allergic Response

Mast cells are an effector cell that plays a pivotal role in type I hypersensitive immune responses. Mast cells exist in connective tissues, such as skin and mucosal tissue, and contain granules which contain bioactive substances such as histamine and heparin in cells. The granules of mast cells are...

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Detalles Bibliográficos
Autores principales: Kim, Su Jeong, Choi, Min Yeong, Min, Keun Young, Jo, Min Geun, Kim, Jie Min, Kim, Hyung Sik, Kim, Young Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622312/
https://www.ncbi.nlm.nih.gov/pubmed/36305292
http://dx.doi.org/10.4062/biomolther.2022.042