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Postmortem Human Dura Mater Cells Exhibit Phenotypic, Transcriptomic and Genetic Abnormalities that Impact their Use for Disease Modeling

Patient-derived cells hold great promise for precision medicine approaches in human health. Human dermal fibroblasts have been a major source of cells for reprogramming and differentiating into specific cell types for disease modeling. Postmortem human dura mater has been suggested as a primary sour...

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Detalles Bibliográficos
Autores principales: Argouarch, Andrea R., Schultz, Nina, Yang, Andrew C., Jang, Yeongjun, Garcia, Kristle, Cosme, Celica G., Corrales, Christian I., Nana, Alissa L., Karydas, Anna M., Spina, Salvatore, Grinberg, Lea T., Miller, Bruce, Wyss-Coray, Tony, Abyzov, Alexej, Goodarzi, Hani, Seeley, William W., Kao, Aimee W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622518/
https://www.ncbi.nlm.nih.gov/pubmed/35809166
http://dx.doi.org/10.1007/s12015-022-10416-x