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Isoflurane has no effect on cognitive or behavioral performance in a mouse model of early-stage Alzheimer’s disease

BACKGROUND: Patients with Alzheimer’s disease show a sex-dependent decline of cognitive and behavioral performance. It is controversially discussed whether general anesthesia itself can aggravate or even cause this neurocognitive decline. Therefore, we investigated the effect of general anesthesia o...

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Detalles Bibliográficos
Autores principales: Borgstedt, Laura, Bratke, Sebastian, Blobner, Manfred, Pötzl, Christoph, Ulm, Bernhard, Jungwirth, Bettina, Schmid, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622753/
https://www.ncbi.nlm.nih.gov/pubmed/36330340
http://dx.doi.org/10.3389/fnins.2022.1033729