Structural and molecular determinants of Candida glabrata metacaspase maturation and activation by calcium

Metacaspases are caspase-like homologs which undergo a complex maturation process involving multiple intra-chain cleavages resulting in a composite enzyme made of a p10 and a p20 domain. Their proteolytic activity involving a cysteine-histidine catalytic dyad, show peptide bond cleavage specificity...

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Detalles Bibliográficos
Autores principales: Conchou, Léa, Doumèche, Bastien, Galisson, Frédéric, Violot, Sébastien, Dugelay, Chloé, Diesis, Eric, Page, Adeline, Bienvenu, Anne-Lise, Picot, Stéphane, Aghajari, Nushin, Ballut, Lionel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622860/
https://www.ncbi.nlm.nih.gov/pubmed/36316540
http://dx.doi.org/10.1038/s42003-022-04091-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622860/
https://www.ncbi.nlm.nih.gov/pubmed/36316540
http://dx.doi.org/10.1038/s42003-022-04091-4

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