MIR retrotransposons link the epigenome and the transcriptome of coding genes in acute myeloid leukemia

DNMT3A and IDH1/2 mutations combinatorically regulate the transcriptome and the epigenome in acute myeloid leukemia; yet the mechanisms of this interplay are unknown. Using a systems approach within topologically associating domains, we find that genes with significant expression-methylation correla...

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Detalles Bibliográficos
Autores principales: Telonis, Aristeidis G., Yang, Qin, Huang, Hsuan-Ting, Figueroa, Maria E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622910/
https://www.ncbi.nlm.nih.gov/pubmed/36316347
http://dx.doi.org/10.1038/s41467-022-34211-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622910/
https://www.ncbi.nlm.nih.gov/pubmed/36316347
http://dx.doi.org/10.1038/s41467-022-34211-x

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