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MIR retrotransposons link the epigenome and the transcriptome of coding genes in acute myeloid leukemia

DNMT3A and IDH1/2 mutations combinatorically regulate the transcriptome and the epigenome in acute myeloid leukemia; yet the mechanisms of this interplay are unknown. Using a systems approach within topologically associating domains, we find that genes with significant expression-methylation correla...

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Detalles Bibliográficos
Autores principales:	Telonis, Aristeidis G., Yang, Qin, Huang, Hsuan-Ting, Figueroa, Maria E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622910/ https://www.ncbi.nlm.nih.gov/pubmed/36316347 http://dx.doi.org/10.1038/s41467-022-34211-x

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