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Prospects for remodeling the hypertrophic heart with myosin modulators

Hypertrophic cardiomyopathy (HCM) is a complex but relatively common genetic disease that usually arises from pathogenic variants that disrupt sarcomere function and lead to variable structural, hypertrophic, and fibrotic remodeling of the heart which result in substantial adverse clinical outcomes...

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Detalles Bibliográficos
Autores principales: Sewanan, Lorenzo R., Shimada, Yuichi J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622926/
https://www.ncbi.nlm.nih.gov/pubmed/36330009
http://dx.doi.org/10.3389/fcvm.2022.1051564