Minocycline intra-bacterial pharmacokinetic hysteresis as a basis for pharmacologic memory and a backbone for once-a-week pan-tuberculosis therapy

Background: There is need for shorter duration regimens for the treatment of tuberculosis, that can treat patients regardless of multidrug resistance status (pan-tuberculosis). Methods: We combined minocycline with tedizolid, moxifloxacin, and rifampin, in the hollow fiber system model of tuberculos...

Descripción completa

Detalles Bibliográficos
Autores principales: Deshpande, Devyani, Srivastava, Shashikant, Pasipanodya, Jotam Garaimunashe, Gumbo, Tawanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622937/
https://www.ncbi.nlm.nih.gov/pubmed/36330086
http://dx.doi.org/10.3389/fphar.2022.1024608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622937/
https://www.ncbi.nlm.nih.gov/pubmed/36330086
http://dx.doi.org/10.3389/fphar.2022.1024608

Ejemplares similares