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Chondrogenic differentiation of human bone marrow MSCs in osteochondral implants under kinematic mechanical load is dependent on the underlying osteo component

Chondrogenic models utilizing human mesenchymal stromal cells (hMSCs) are often simplistic, with a single cell type and the absence of mechanical stimulation. Considering the articulating joint as an organ it would be beneficial to include more complex stimulation. Within this study we applied clini...

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Detalles Bibliográficos
Autores principales: Monaco, Graziana, Qawasmi, Feras, El Haj, Alicia J., Forsyth, Nicolas R., Stoddart, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622941/
https://www.ncbi.nlm.nih.gov/pubmed/36329702
http://dx.doi.org/10.3389/fbioe.2022.998774